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Theileria annulata histone deacetylase 1 (TaHDAC1) initiates schizont to merozoite stage conversion
A fungal metabolite, FR235222, specifically inhibits a histone deacetylase of the apicomplexan parasite Toxoplasma gondii and TgHDAC3 has emerged as a key factor regulating developmental stage transition in this species. Here, we exploited FR235222 to ask if changes in histone acetylation regulate d...
Autores principales: | Tajeri, Shahin, Momeux, Laurence, Saintpierre, Benjamin, Mfarrej, Sara, Chapple, Alexander, Mourier, Tobias, Shiels, Brian, Ariey, Frédéric, Pain, Arnab, Langsley, Gordon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325746/ https://www.ncbi.nlm.nih.gov/pubmed/35882887 http://dx.doi.org/10.1038/s41598-022-15518-7 |
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