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Molecular mechanism of toxin neutralization in the HipBST toxin-antitoxin system of Legionella pneumophila
Toxin-antitoxin (TA) systems are ubiquitous genetic modules in bacteria and archaea. Here, we perform structural and biochemical characterization of the Legionella pneumophila effector Lpg2370, demonstrating that it is a Ser/Thr kinase. Together with two upstream genes, lpg2370 constitutes the tripa...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325769/ https://www.ncbi.nlm.nih.gov/pubmed/35882877 http://dx.doi.org/10.1038/s41467-022-32049-x |