Molecular mechanism of toxin neutralization in the HipBST toxin-antitoxin system of Legionella pneumophila

Toxin-antitoxin (TA) systems are ubiquitous genetic modules in bacteria and archaea. Here, we perform structural and biochemical characterization of the Legionella pneumophila effector Lpg2370, demonstrating that it is a Ser/Thr kinase. Together with two upstream genes, lpg2370 constitutes the tripa...

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Detalles Bibliográficos
Autores principales: Zhen, Xiangkai, Wu, Yongyu, Ge, Jinli, Fu, Jiaqi, Ye, Le, Lin, Niannian, Huang, Zhijie, Liu, Zihe, Luo, Zhao-qing, Qiu, Jiazhang, Ouyang, Songying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325769/
https://www.ncbi.nlm.nih.gov/pubmed/35882877
http://dx.doi.org/10.1038/s41467-022-32049-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325769/
https://www.ncbi.nlm.nih.gov/pubmed/35882877
http://dx.doi.org/10.1038/s41467-022-32049-x

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