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Exploiting gene dependency to inform drug development for multiple myeloma

Despite recent advances in therapy, multiple myeloma essentially remains an incurable malignancy. Targeting tumour-specific essential genes, which constitute a druggable dependency, potentially offers a strategy for developing new therapeutic agents to treat MM and overcome drug resistance. To explo...

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Detalles Bibliográficos
Autores principales: Went, Molly, Hoang, Phuc H., Law, Philip J., Kaiser, Martin F., Houlston, Richard S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325789/
https://www.ncbi.nlm.nih.gov/pubmed/35882937
http://dx.doi.org/10.1038/s41598-022-16940-7