Genotoxicity of methyl acrylate and ethyl acrylate and its relationship with glutathione

Methyl acrylate (MA) and ethyl acrylate (EA) had previously tested positive for mutagenicity in vitro, but in vivo studies were negative. One of the metabolism pathways of alkyl acrylates is conjugation with glutathione. The glutathione availability is restricted in standard in vitro test systems so...

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Detalles Bibliográficos
Autores principales: Oesch, F., Honarvar, N., Fabian, E., Finch, L., Hindle, S., Wiench, K., Landsiedel, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Genotoxicity and Carcinogenicity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325804/
https://www.ncbi.nlm.nih.gov/pubmed/35704047
http://dx.doi.org/10.1007/s00204-022-03322-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325804/
https://www.ncbi.nlm.nih.gov/pubmed/35704047
http://dx.doi.org/10.1007/s00204-022-03322-1

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