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Cell death induction in Aspergillus fumigatus: accentuating drug toxicity through inhibition of the unfolded protein response (UPR)

One of the most potent opportunistic fungal pathogens of humans is Aspergillus fumigatus, an environmental mold that causes a life-threatening pneumonia with a high rate of morbidity and mortality. Despite advances in therapy, issues of drug toxicity and antifungal resistance remain an obstacle to e...

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Detalles Bibliográficos
Autores principales: Guirao-Abad, José P., Weichert, Martin, Askew, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325865/
https://www.ncbi.nlm.nih.gov/pubmed/35909601
http://dx.doi.org/10.1016/j.crmicr.2022.100119