Aggregative trans-eQTL analysis detects trait-specific target gene sets in whole blood

Large scale genetic association studies have identified many trait-associated variants and understanding the role of these variants in the downstream regulation of gene-expressions can uncover important mediating biological mechanisms. Here we propose ARCHIE, a summary statistic based sparse canonic...

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Detalles Bibliográficos
Autores principales: Dutta, Diptavo, He, Yuan, Saha, Ashis, Arvanitis, Marios, Battle, Alexis, Chatterjee, Nilanjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325868/
https://www.ncbi.nlm.nih.gov/pubmed/35882830
http://dx.doi.org/10.1038/s41467-022-31845-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325868/
https://www.ncbi.nlm.nih.gov/pubmed/35882830
http://dx.doi.org/10.1038/s41467-022-31845-9

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