Cargando…

TRPM7 deficiency exacerbates cardiovascular and renal damage induced by aldosterone-salt

Hyperaldosteronism causes cardiovascular disease as well as hypomagnesemia. Mechanisms are ill-defined but dysregulation of TRPM7, a Mg(2+)-permeable channel/α-kinase, may be important. We examined the role of TRPM7 in aldosterone-dependent cardiovascular and renal injury by studying aldosterone-sal...

Descripción completa

Detalles Bibliográficos
Autores principales: Rios, Francisco J., Zou, Zhi-Guo, Harvey, Adam P., Harvey, Katie Y., Camargo, Livia L., Neves, Karla B., Nichol, Sarah E. F., Alves-Lopes, Rheure, Cheah, Alexius, Zahraa, Maram, Ryazanov, Alexey G., Ryazanova, Lillia, Gudermann, Thomas, Chubanov, Vladimir, Montezano, Augusto C., Touyz, Rhian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325869/
https://www.ncbi.nlm.nih.gov/pubmed/35882956
http://dx.doi.org/10.1038/s42003-022-03715-z