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TRPM7 deficiency exacerbates cardiovascular and renal damage induced by aldosterone-salt
Hyperaldosteronism causes cardiovascular disease as well as hypomagnesemia. Mechanisms are ill-defined but dysregulation of TRPM7, a Mg(2+)-permeable channel/α-kinase, may be important. We examined the role of TRPM7 in aldosterone-dependent cardiovascular and renal injury by studying aldosterone-sal...
Autores principales: | Rios, Francisco J., Zou, Zhi-Guo, Harvey, Adam P., Harvey, Katie Y., Camargo, Livia L., Neves, Karla B., Nichol, Sarah E. F., Alves-Lopes, Rheure, Cheah, Alexius, Zahraa, Maram, Ryazanov, Alexey G., Ryazanova, Lillia, Gudermann, Thomas, Chubanov, Vladimir, Montezano, Augusto C., Touyz, Rhian M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325869/ https://www.ncbi.nlm.nih.gov/pubmed/35882956 http://dx.doi.org/10.1038/s42003-022-03715-z |
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