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Persistent popliteal lymphatic muscle cell coverage defects despite amelioration of arthritis and recovery of popliteal lymphatic vessel function in TNF-Tg mice following anti-TNF therapy

While rheumatoid arthritis patients and tumor necrosis factor transgenic (TNF-Tg) mice with inflammatory-erosive arthritis display lymphatic drainage deficits, the mechanisms responsible remain unknown. As ultrastructural studies of joint-draining popliteal lymphatic vessels (PLVs) in TNF-Tg mice re...

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Detalles Bibliográficos
Autores principales: Kenney, H. Mark, Peng, Yue, Bell, Richard D., Wood, Ronald W., Xing, Lianping, Ritchlin, Christopher T., Schwarz, Edward M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325893/
https://www.ncbi.nlm.nih.gov/pubmed/35882971
http://dx.doi.org/10.1038/s41598-022-16884-y