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A biepitope, adjuvant-free, self-assembled influenza nanovaccine provides cross-protection against H3N2 and H1N1 viruses in mice

Currently, the incorporation of multiple epitopes into vaccines is more desirable than the incorporation of a single antigen for universal influenza vaccine development. However, epitopes induce poor immune responses. Although the use of adjuvants can overcome this obstacle, it may raise new problem...

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Detalles Bibliográficos
Autores principales: Qiao, Yongbo, Zhang, YaXin, Chen, Jie, Jin, Shenghui, Shan, Yaming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tsinghua University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325945/
https://www.ncbi.nlm.nih.gov/pubmed/35911479
http://dx.doi.org/10.1007/s12274-022-4482-4