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Replacement of Mouse Microglia With Human Induced Pluripotent Stem Cell (hiPSC)-Derived Microglia in Mouse Organotypic Slice Cultures

Microglia, the major immune cells in the brain, are reported to differ in gene expression patterns among species. Therefore, it would be preferable in some cases to use human microglia rather than mouse microglia in microglia-targeted disease research. In the past half a decade, researchers have dev...

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Detalles Bibliográficos
Autores principales: Ogaki, Ari, Ikegaya, Yuji, Koyama, Ryuta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325970/
https://www.ncbi.nlm.nih.gov/pubmed/35910250
http://dx.doi.org/10.3389/fncel.2022.918442