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Folate Carrier Deficiency Drives Differential Methylation and Enhanced Cellular Potency in the Neural Plate Border

The neural plate border (NPB) of vertebrate embryos segregates from the neural and epidermal regions, and it is comprised of an intermingled group of multipotent progenitor cells. Folate is the precursor of S-adenosylmethionine, the main methyl donor for DNA methylation, and it is critical for embry...

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Detalles Bibliográficos
Autores principales: Alata Jimenez, Nagif, Strobl-Mazzulla, Pablo H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326018/
https://www.ncbi.nlm.nih.gov/pubmed/35912103
http://dx.doi.org/10.3389/fcell.2022.834625