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BNIP3 Upregulation Characterizes Cancer Cell Subpopulation With Increased Fitness and Proliferation

BNIP3 is a BH3-only protein with both pro-apoptotic and pro-survival roles depending on the cellular context. It remains unclear how BNIP3 RNA level dictates cell fate decisions of cancer cells. Here, we undertook a quantitative analysis of BNIP3 expression and functions in single-cell datasets of v...

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Detalles Bibliográficos
Autores principales: Zhu, Yanyan, Chen, Bowang, Yan, Junya, Zhao, Wendi, Dou, Pengli, Sun, Na, Wang, Yaokai, Huang, Xiaoyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326071/
https://www.ncbi.nlm.nih.gov/pubmed/35912211
http://dx.doi.org/10.3389/fonc.2022.923890