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Type I Interferons Promote Germinal Centers Through B Cell Intrinsic Signaling and Dendritic Cell Dependent Th1 and Tfh Cell Lineages

Type I interferons (IFNs) are essential for antiviral immunity, appear to represent a key component of mRNA vaccine-adjuvanticity, and correlate with severity of systemic autoimmune disease. Relevant to all, type I IFNs can enhance germinal center (GC) B cell responses but underlying signaling pathw...

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Detalles Bibliográficos
Autores principales: Dahlgren, Madelene W., Plumb, Adam W., Niss, Kristoffer, Lahl, Katharina, Brunak, Søren, Johansson-Lindbom, Bengt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326081/
https://www.ncbi.nlm.nih.gov/pubmed/35911733
http://dx.doi.org/10.3389/fimmu.2022.932388