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Targeting of the Lipid Metabolism Impairs Resistance to BRAF Kinase Inhibitor in Melanoma

Drug resistance limits the achievement of persistent cures for the treatment of melanoma, in spite of the efficacy of the available drugs. The aim of the present study was to explore the involvement of lipid metabolism in melanoma resistance and assess the effects of its targeting in cellular models...

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Detalles Bibliográficos
Autores principales: Vergani, Elisabetta, Beretta, Giovanni L., Aloisi, Mariachiara, Costantino, Matteo, Corno, Cristina, Frigerio, Simona, Tinelli, Stella, Dugo, Matteo, Accattatis, Felice Maria, Granata, Agnese, Arnaboldi, Lorenzo, Rodolfo, Monica, Perego, Paola, Gatti, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326082/
https://www.ncbi.nlm.nih.gov/pubmed/35912092
http://dx.doi.org/10.3389/fcell.2022.927118