Sulfated Fucogalactan From Laminaria Japonica Ameliorates β-Cell Failure by Attenuating Mitochondrial Dysfunction via SIRT1–PGC1-α Signaling Pathway Activation

As mitochondrial metabolism is a major determinant of β-cell insulin secretion, mitochondrial dysfunction underlies β-cell failure and type 2 diabetes mellitus progression. An algal polysaccharide of Laminaria japonica, sulfated fucogalactan (SFG) displays various pharmacological effects in a variet...

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Detalles Bibliográficos
Autores principales: Wu, Nan, Jin, Weihua, Zhao, Yuchen, Wang, Hong, He, Sunyue, Zhang, Wenjing, Zhou, Jiaqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326112/
https://www.ncbi.nlm.nih.gov/pubmed/35909530
http://dx.doi.org/10.3389/fendo.2022.881256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326112/
https://www.ncbi.nlm.nih.gov/pubmed/35909530
http://dx.doi.org/10.3389/fendo.2022.881256

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