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Treatment of Cardiovascular Dysfunction with PDE3-Inhibitors in Moderate and Severe Hypothermia—Effects on Cellular Elimination of Cyclic Adenosine Monophosphate and Cyclic Guanosine Monophosphate

Introduction: Rewarming from accidental hypothermia is often complicated by hypothermia-induced cardiovascular dysfunction, which could lead to shock. Current guidelines do not recommend any pharmacological treatment at core temperatures below 30°C, due to lack of knowledge. However, previous in viv...

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Detalles Bibliográficos
Autores principales: Kuzmiszyn, Adrina Kalasho, Selli, Anders Lund, Smaglyukova, Natalia, Kondratiev, Timofei, Fuskevåg, Ole-Martin, Lyså, Roy Andre, Ravna, Aina Westrheim, Tveita, Torkjel, Sager, Georg, Dietrichs, Erik Sveberg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326216/
https://www.ncbi.nlm.nih.gov/pubmed/35910566
http://dx.doi.org/10.3389/fphys.2022.923091