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A Novel Role of PP2A Methylation in the Regulation of Tight Junction Assembly and Integrity

Tight junctions (TJs) are multiprotein complexes essential for cell polarity and the barrier function of epithelia. The major signaling molecule, protein serine/threonine phosphatase 2A (PP2A), interacts with the TJ and modulates the phosphorylation state of TJ proteins. An important PP2A regulatory...

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Detalles Bibliográficos
Autores principales: Schuhmacher, Diana, Sontag, Jean-Marie, Sontag, Estelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326217/
https://www.ncbi.nlm.nih.gov/pubmed/35912112
http://dx.doi.org/10.3389/fcell.2022.911279