MRI Markers of Small Vessel Disease and the APOE Allele in Cognitive Impairment

OBJECTIVE: The apolipoprotein E (APOE) ε4 allele is the main genetic risk factor for dementia and Alzheimer's disease (AD), but the underlying mechanism for the increased risk is not well understood. Cerebral small vessel disease (SVD) is prevalent among patients with cognitive impairment and i...

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Detalles Bibliográficos
Autores principales: Shams, Mana, Shams, Sara, Martola, Juha, Cavallin, Lena, Granberg, Tobias, Kaijser, Magnus, Wintermark, Max, Westman, Eric, Aspelin, Peter, Kristoffersen Wiberg, Maria, Wahlund, Lars-Olof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326313/
https://www.ncbi.nlm.nih.gov/pubmed/35912087
http://dx.doi.org/10.3389/fnagi.2022.897674