MRI Markers of Small Vessel Disease and the APOE Allele in Cognitive Impairment
OBJECTIVE: The apolipoprotein E (APOE) ε4 allele is the main genetic risk factor for dementia and Alzheimer's disease (AD), but the underlying mechanism for the increased risk is not well understood. Cerebral small vessel disease (SVD) is prevalent among patients with cognitive impairment and i...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326313/ https://www.ncbi.nlm.nih.gov/pubmed/35912087 http://dx.doi.org/10.3389/fnagi.2022.897674 |