Multi-mtDNA Variants May Be a Factor Contributing to Mitochondrial Function Variety in the Skin-Derived Fibroblasts of Leber's Hereditary Optic Neuropathy Patients

Heterogeneity is a major feature of Leber's hereditary optic neuropathy (LHON) and has a significant impact on the manifestation and diagnosis of the disease. This study explored whether multiple variations in mitochondrial genes were associated with the heterogeneity, mainly phenotypic heterog...

Descripción completa

Detalles Bibliográficos
Autores principales: Yao, Shun, Zhou, Qingru, Yang, Mingzhu, Li, Ya, Jin, Xiuxiu, Guo, Qingge, Yang, Lin, Qin, Fangyuan, Lei, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326446/
https://www.ncbi.nlm.nih.gov/pubmed/35909448
http://dx.doi.org/10.3389/fnmol.2022.920221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326446/
https://www.ncbi.nlm.nih.gov/pubmed/35909448
http://dx.doi.org/10.3389/fnmol.2022.920221

Ejemplares similares