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Telomere Attrition With Concomitant hTERT Overexpression Involved in the Progression of Gastric Cancer May Have Prognostic and Clinical Implications in High-Risk Population Group From North India

Genetic instabilities exacerbated by the dysfunction of telomeres can lead to the development of cancer. Nearly 90% of all human malignancies are linked with telomere dysregulation and overexpression of telomerase, an enzyme that catalyzes the synthesis of telomeric DNA repeats at the ends of chromo...

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Detalles Bibliográficos
Autores principales: Mushtaq, Ifra, Bhat, Gh Rasool, Rah, Bilal, Besina, Syed, Zahoor, Sheikh, Wani, Muneer A., Shah, Mubashir A., Bashir, Sadaf, Farooq, Muzamil, Rather, Rafiq A., Afroze, Dil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326504/
https://www.ncbi.nlm.nih.gov/pubmed/35912187
http://dx.doi.org/10.3389/fonc.2022.919351