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l‐Carnitine therapy improves right heart dysfunction through Cpt1‐dependent fatty acid oxidation

Pulmonary arterial hypertension (PAH) is a fatal vasculopathy that ultimately leads to elevated pulmonary pressure and death by right ventricular (RV) failure, which occurs in part due to decreased fatty acid oxidation and cytotoxic lipid accumulation. In this study, we tested the hypothesis that de...

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Detalles Bibliográficos
Autores principales: Agrawal, Vineet, Hemnes, Anna R., Shelburne, Nicholas J., Fortune, Niki, Fuentes, Julio L., Colvin, Dan, Calcutt, Marion W., Talati, Megha, Poovey, Emily, West, James D., Brittain, Evan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326551/
https://www.ncbi.nlm.nih.gov/pubmed/35911183
http://dx.doi.org/10.1002/pul2.12107