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Enhancing co-stimulation of CAR T cells to improve treatment outcomes in solid cancers

Co-stimulation is a fundamental component of T cell biology and plays a key role in determining the quality of T cell proliferation, differentiation, and memory formation. T cell-based immunotherapies, such as chimeric antigen receptor (CAR) T cell immunotherapy, are no exception. Solid tumours have...

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Detalles Bibliográficos
Autores principales: Harrison, Aaron J, Du, Xin, von Scheidt, Bianca, Kershaw, Michael H, Slaney, Clare Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327106/
https://www.ncbi.nlm.nih.gov/pubmed/35919743
http://dx.doi.org/10.1093/immadv/ltab016