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miR-126-3p containing exosomes derived from human umbilical cord mesenchymal stem cells promote angiogenesis and attenuate ovarian granulosa cell apoptosis in a preclinical rat model of premature ovarian failure

BACKGROUND: In our previous research, we found that overexpression of miR-126-3p in human umbilical cord MSCs (hucMSCs) promoted human umbilical vein endothelial cells angiogenic activities through exosome-mediated mechanisms. The present study aimed to investigate the role of miR-126-3p-modified hu...

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Detalles Bibliográficos
Autores principales: Qu, Qingxi, Liu, Linghong, Cui, Yuqian, Liu, Hongli, Yi, Jingyang, Bing, Weidong, Liu, Chunxiao, Jiang, Detian, Bi, Yanwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327169/
https://www.ncbi.nlm.nih.gov/pubmed/35883161
http://dx.doi.org/10.1186/s13287-022-03056-y