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DNA methylation-mediated differential expression of DLX4 isoforms has opposing roles in leukemogenesis

BACKGROUND: Previously, we reported the expression of DLX4 isoforms (BP1 and DLX7) in myeloid leukemia, but the functional role of DLX4 isoforms remains poorly understood. In the work described herein, we further determined the underlying role of DLX4 isoforms in chronic myeloid leukemia (CML) leuke...

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Detalles Bibliográficos
Autores principales: Zhou, Jing-dong, Zhao, Yang-jing, Leng, Jia-yan, Gu, Yu, Xu, Zi-jun, Ma, Ji-chun, Wen, Xiang-mei, Lin, Jiang, Zhang, Ting-juan, Qian, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327205/
https://www.ncbi.nlm.nih.gov/pubmed/35883028
http://dx.doi.org/10.1186/s11658-022-00358-0