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Drug-free in vitro activation combined with 3D-bioprinted adipose-derived stem cells restores ovarian function of rats with premature ovarian insufficiency

BACKGROUND: Emerging drug-free in vitro activation (IVA) technique enables patients with premature ovarian insufficiency (POI) to restore ovarian function and conceive their own genetic offspring. However, various issues have greatly restricted its clinical application. Transplantation of adipose-de...

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Detalles Bibliográficos
Autores principales: Li, Qian, Zheng, Jiahua, Li, Zhongkang, Xiao, Yanlai, Zhang, Mingle, Shi, Wenxin, Gao, He, Huang, Xianghua, Zhang, Jingkun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327214/
https://www.ncbi.nlm.nih.gov/pubmed/35883196
http://dx.doi.org/10.1186/s13287-022-03035-3