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Drug-free in vitro activation combined with 3D-bioprinted adipose-derived stem cells restores ovarian function of rats with premature ovarian insufficiency
BACKGROUND: Emerging drug-free in vitro activation (IVA) technique enables patients with premature ovarian insufficiency (POI) to restore ovarian function and conceive their own genetic offspring. However, various issues have greatly restricted its clinical application. Transplantation of adipose-de...
Autores principales: | Li, Qian, Zheng, Jiahua, Li, Zhongkang, Xiao, Yanlai, Zhang, Mingle, Shi, Wenxin, Gao, He, Huang, Xianghua, Zhang, Jingkun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327214/ https://www.ncbi.nlm.nih.gov/pubmed/35883196 http://dx.doi.org/10.1186/s13287-022-03035-3 |
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