Cargando…

d-Borneol enhances cisplatin sensitivity via p21/p27-mediated S-phase arrest and cell apoptosis in non-small cell lung cancer cells and a murine xenograft model

BACKGROUND: Cisplatin (CDDP) is commonly used to treat non-small cell lung cancer (NSCLC), but the appearance of drug resistance greatly hinders its efficacy. Borneol may promote drug absorption; however, synergism between borneol and CDDP in suppressing NSCLC is not clearly understood. Hence, we in...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Jinxiu, Yuan, Jianmei, Li, Yong, Wang, Jian, Gong, Daoyin, Xie, Qian, Ma, Rong, Wang, Jiajun, Ren, Mihong, Lu, Danni, Xu, Zhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327246/
https://www.ncbi.nlm.nih.gov/pubmed/35883026
http://dx.doi.org/10.1186/s11658-022-00362-4