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C/EBPα regulates the fate of bone marrow mesenchymal stem cells and steroid-induced avascular necrosis of the femoral head by targeting the PPARγ signalling pathway

BACKGROUND: The imbalance of osteogenic/adipogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) is closely related to steroid-induced avascular necrosis of the femoral head (SANFH). We aimed to investigate the epigenetic mechanism of intramedullary fat accumulation and continuous os...

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Detalles Bibliográficos
Autores principales: Duan, Ping, Wang, Hanyu, Yi, Xinzeyu, Zhang, Hao, Chen, Hui, Pan, Zhenyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327281/
https://www.ncbi.nlm.nih.gov/pubmed/35883192
http://dx.doi.org/10.1186/s13287-022-03027-3