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Torsional behaviour of supercoiled DNA regulates recognition of architectural protein Fis on minicircle DNA
Three-dimensional genome organization is indispensable for regulating its functions. Experimental techniques based on the proximity ligation principle have identified spatially segregated domains at a sub-megabase level. The transcriptional activity of these domains is strongly coupled with the supe...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327302/ http://dx.doi.org/10.1093/nar/gkac522 |