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Meiosis resumption in human primordial germ cells from induced pluripotent stem cells by in vitro activation and reconstruction of ovarian nests

BACKGROUND: The differentiation of human induced pluripotent stem cells (iPSCs) into oocytes, which involves the transformation from mitosis to meiosis, has been a hotspot of biological research for many years and represents a desirable experimental model and potential strategy for treating infertil...

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Detalles Bibliográficos
Autores principales: Yang, Sheng, Liu, Zhen, Wu, Shengda, Zou, Lang, Cao, Yanpei, Xu, Hongjia, Huang, Jingfeng, Tian, Qingyan, Wu, Fanggui, Li, Panpan, Peng, Shuping, Shuai, Cijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327357/
https://www.ncbi.nlm.nih.gov/pubmed/35883163
http://dx.doi.org/10.1186/s13287-022-03019-3