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Activation of peripheral TRPM8 mitigates ischemic stroke by topically applied menthol

BACKGROUND: No reports exist as to neuroprotective effects associated with topical activation of transient receptor potential melastatin 8 (TRPM8), a noted cold receptor. In the present study, we identified whether activating peripheral TRPM8 can be an adjuvant therapy for ischemic stroke. METHODS:...

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Detalles Bibliográficos
Autores principales: Huang, Shiang-Suo, Su, Hsing-Hui, Chien, Szu-Yu, Chung, Hsin-Yi, Luo, Sih-Ting, Chu, Yu-Ting, Wang, Yi-Hsin, MacDonald, Iona J., Lee, Hsun-Hua, Chen, Yi-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327358/
https://www.ncbi.nlm.nih.gov/pubmed/35897101
http://dx.doi.org/10.1186/s12974-022-02553-4