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Multivariate estimation of factor structures of complex traits using SNP-based genomic relationships

BACKGROUND: Heritability and genetic correlation can be estimated from genome-wide single-nucleotide polymorphism (SNP) data using various methods. We recently developed multivariate genomic-relatedness-based restricted maximum likelihood (MGREML) for statistically and computationally efficient esti...

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Detalles Bibliográficos
Autores principales: De Vlaming, Ronald, Slob, Eric A. W., Groenen, Patrick J. F., Rietveld, Cornelius A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327374/
https://www.ncbi.nlm.nih.gov/pubmed/35896974
http://dx.doi.org/10.1186/s12859-022-04835-3