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Mesenchymal stem cells improve liver fibrosis and protect hepatocytes by promoting microRNA-148a-5p-mediated inhibition of Notch signaling pathway

BACKGROUND: Mesenchymal stem cells (MSCs) are considered to be a potential therapeutic tool for liver fibrosis. Inhibiting the activation of hepatic stellate cells (HSCs) and protecting hepatocytes are important mechanisms for the anti-fibrotic effect of MSCs. However, how MSCs inhibit liver fibrosi...

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Detalles Bibliográficos
Autores principales: Zhou, Qing, Rong, Chao, Gu, Tengfei, Li, Hongda, Wu, Lei, Zhuansun, Xuemei, Zhao, Xin, Xiao, Zuorun, Kuang, Yuting, Xu, Sanrong, Wang, Shouli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327397/
https://www.ncbi.nlm.nih.gov/pubmed/35883205
http://dx.doi.org/10.1186/s13287-022-03030-8