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Mesenchymal stem cells improve liver fibrosis and protect hepatocytes by promoting microRNA-148a-5p-mediated inhibition of Notch signaling pathway
BACKGROUND: Mesenchymal stem cells (MSCs) are considered to be a potential therapeutic tool for liver fibrosis. Inhibiting the activation of hepatic stellate cells (HSCs) and protecting hepatocytes are important mechanisms for the anti-fibrotic effect of MSCs. However, how MSCs inhibit liver fibrosi...
Autores principales: | Zhou, Qing, Rong, Chao, Gu, Tengfei, Li, Hongda, Wu, Lei, Zhuansun, Xuemei, Zhao, Xin, Xiao, Zuorun, Kuang, Yuting, Xu, Sanrong, Wang, Shouli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327397/ https://www.ncbi.nlm.nih.gov/pubmed/35883205 http://dx.doi.org/10.1186/s13287-022-03030-8 |
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