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Engineering chimeric antigen receptor neutrophils from human pluripotent stem cells for targeted cancer immunotherapy
Neutrophils, the most abundant white blood cells in circulation, are closely related to cancer development and progression. Healthy primary neutrophils present potent cytotoxicity against various cancer cell lines through direct contact and via generation of reactive oxygen species. However, due to...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327527/ https://www.ncbi.nlm.nih.gov/pubmed/35858579 http://dx.doi.org/10.1016/j.celrep.2022.111128 |