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Engineering chimeric antigen receptor neutrophils from human pluripotent stem cells for targeted cancer immunotherapy

Neutrophils, the most abundant white blood cells in circulation, are closely related to cancer development and progression. Healthy primary neutrophils present potent cytotoxicity against various cancer cell lines through direct contact and via generation of reactive oxygen species. However, due to...

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Detalles Bibliográficos
Autores principales: Chang, Yun, Syahirah, Ramizah, Wang, Xuepeng, Jin, Gyuhyung, Torregrosa-Allen, Sandra, Elzey, Bennett D., Hummel, Sydney N., Wang, Tianqi, Li, Can, Lian, Xiaojun, Deng, Qing, Broxmeyer, Hal E., Bao, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327527/
https://www.ncbi.nlm.nih.gov/pubmed/35858579
http://dx.doi.org/10.1016/j.celrep.2022.111128