Genome-wide association study of platelet factor 4/heparin antibodies in heparin-induced thrombocytopenia

Heparin, a widely used anticoagulant, carries the risk of an antibody-mediated adverse drug reaction, heparin-induced thrombocytopenia (HIT). A subset of heparin-treated patients produces detectable levels of antibodies against complexes of heparin bound to circulating platelet factor 4 (PF4). Using...

Descripción completa

Detalles Bibliográficos
Autores principales: Giles, Jason B., Steiner, Heidi E., Rollin, Jerome, Shaffer, Christian M., Momozawa, Yukihide, Mushiroda, Taisei, Inai, Chihiro, Selleng, Kathleen, Thiele, Thomas, Pouplard, Claire, Heddle, Nancy M., Kubo, Michiaki, Miller, Elise C., Martinez, Kiana L., Phillips, Elizabeth J., Warkentin, Theodore E., Gruel, Yves, Greinacher, Andreas, Roden, Dan M., Karnes, Jason H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Platelets and Thrombopoiesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327558/
https://www.ncbi.nlm.nih.gov/pubmed/35533259
http://dx.doi.org/10.1182/bloodadvances.2022007673

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327558/
https://www.ncbi.nlm.nih.gov/pubmed/35533259
http://dx.doi.org/10.1182/bloodadvances.2022007673

Ejemplares similares