Optimized peptide extraction method for analysis of antimicrobial peptide Kn2-7/dKn2-7 stability in human serum by LC–MS

AIM: To develop an extraction protocol and determine stability for antimicrobial peptide (AMP) Kn2-7 and its d-enantiomer dKn2-7 in human serum. MATERIALS & METHODS: We compared use of ethanol, acetonitrile, RapiGest SF Surfactant and 1% formic acid in ethanol for AMP recovery from serum prior t...

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Detalles Bibliográficos
Autores principales: Chen, Wen, Kirui, Dickson, Millenbaugh, Nancy J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2022
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327644/
https://www.ncbi.nlm.nih.gov/pubmed/35909998
http://dx.doi.org/10.2144/fsoa-2022-0013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327644/
https://www.ncbi.nlm.nih.gov/pubmed/35909998
http://dx.doi.org/10.2144/fsoa-2022-0013

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