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Optimized peptide extraction method for analysis of antimicrobial peptide Kn2-7/dKn2-7 stability in human serum by LC–MS
AIM: To develop an extraction protocol and determine stability for antimicrobial peptide (AMP) Kn2-7 and its d-enantiomer dKn2-7 in human serum. MATERIALS & METHODS: We compared use of ethanol, acetonitrile, RapiGest SF Surfactant and 1% formic acid in ethanol for AMP recovery from serum prior t...
Autores principales: | Chen, Wen, Kirui, Dickson, Millenbaugh, Nancy J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Future Science Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327644/ https://www.ncbi.nlm.nih.gov/pubmed/35909998 http://dx.doi.org/10.2144/fsoa-2022-0013 |
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