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Endocytosed HIV-1 Envelope Glycoprotein Traffics to Rab14(+) Late Endosomes and Lysosomes to Regulate Surface Levels in T-Cell Lines
Production of infectious HIV-1 particles requires incorporation of the viral envelope glycoprotein (Env) at the plasma membrane (PM) of infected CD4(+) T cells. Env trafficking to the PM exposes viral epitopes that can be exploited by the host immune system; however, HIV-1 can evade this response by...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Microbiology
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327703/ https://www.ncbi.nlm.nih.gov/pubmed/35770989 http://dx.doi.org/10.1128/jvi.00767-22 |