Removal of the E(rns) RNase Activity and of the 3′ Untranslated Region Polyuridine Insertion in a Low-Virulence Classical Swine Fever Virus Triggers a Cytokine Storm and Lethal Disease

In this study, we assessed the potential synergistic effect of the E(rns) RNase activity and the poly-U insertion in the 3′ untranslated region (UTR) of the low-virulence classical swine fever virus (CSFV) isolate Pinar de Rio (PdR) in innate and adaptive immunity regulation and its relationship wit...

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Detalles Bibliográficos
Autores principales: Wang, Miaomiao, Bohórquez, José Alejandro, Muñoz-González, Sara, Gerber, Markus, Alberch, Mònica, Pérez-Simó, Marta, Abad, Xavier, Liniger, Matthias, Ruggli, Nicolas, Ganges, Llilianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327722/
https://www.ncbi.nlm.nih.gov/pubmed/35758667
http://dx.doi.org/10.1128/jvi.00438-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327722/
https://www.ncbi.nlm.nih.gov/pubmed/35758667
http://dx.doi.org/10.1128/jvi.00438-22

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