Inborn errors of immunity caused by defects in the DNA damage response pathways: Importance of minimizing treatment‐related genotoxicity

Several primary immunodeficiencies are caused by defects in the general DNA repair machinery as exemplified by the T‐B‐ radiosensitive SCID condition owing to impaired resolution of programmed DNA double‐strand breaks introduced by RAG1/2 during V(D)J recombination. The genome instability generally...

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Detalles Bibliográficos
Autores principales: Fournier, Benjamin, Mahlaoui, Nizar, Moshous, Despina, de Villartay, Jean‐Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327728/
https://www.ncbi.nlm.nih.gov/pubmed/35754136
http://dx.doi.org/10.1111/pai.13820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327728/
https://www.ncbi.nlm.nih.gov/pubmed/35754136
http://dx.doi.org/10.1111/pai.13820

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