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IL-6-Driven pSTAT1 Response Is Linked to T Cell Features Implicated in Early Immune Dysregulation

Elevated levels and enhanced sensing of the pro-inflammatory cytokine interleukin-6 (IL-6) are key features of many autoimmune and inflammatory diseases. To better understand how IL-6 signaling may influence human T cell fate, we investigated the relationships between levels of components of the IL-...

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Detalles Bibliográficos
Autores principales: Lambert, Katharina, Diggins, Kirsten E., Jones, Britta E., Hundhausen, Christian, Maerz, Megan D., Hocking, Anne M., Sanda, Srinath, Greenbaum, Carla J., Linsley, Peter S., Cerosaletti, Karen, Buckner, Jane H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327741/
https://www.ncbi.nlm.nih.gov/pubmed/35911690
http://dx.doi.org/10.3389/fimmu.2022.935394