An integrated PK‐PD model for cortisol and the 17‐hydroxyprogesterone and androstenedione biomarkers in children with congenital adrenal hyperplasia

AIMS: The aim of this study was to characterize the pharmacokinetic/pharmacodynamic relationships of cortisol and the adrenal biomarkers 17‐hydroxyprogesterone and androstenedione in children with congenital adrenal hyperplasia (CAH). METHODS: A nonlinear mixed‐effect modelling approach was used to...

Descripción completa

Detalles Bibliográficos
Autores principales: Al‐Kofahi, Mahmoud, Ahmed, Mariam A., Jaber, Mutaz M., Tran, Thang N., Willis, Brian A., Zimmerman, Cheryl L., Gonzalez‐Bolanos, Maria T., Brundage, Richard C., Sarafoglou, Kyriakie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9328191/
https://www.ncbi.nlm.nih.gov/pubmed/32652643
http://dx.doi.org/10.1111/bcp.14470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9328191/
https://www.ncbi.nlm.nih.gov/pubmed/32652643
http://dx.doi.org/10.1111/bcp.14470

Ejemplares similares