Therapeutic index of inhaled corticosteroids in asthma: A dose–response comparison on airway hyperresponsiveness and adrenal axis suppression

AIMS: To compare the airway potency, systemic activity and therapeutic index of three inhaled corticosteroids that differ in glucocorticoid receptor binding affinity, physicochemical and pharmacokinetic properties. METHODS: This escalating‐dose, placebo‐controlled, cross‐over study randomised adults...

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Detalles Bibliográficos
Autores principales: Daley‐Yates, Peter, Brealey, Noushin, Thomas, Sebin, Austin, Daren, Shabbir, Shaila, Harrison, Tim, Singh, Dave, Barnes, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9328361/
https://www.ncbi.nlm.nih.gov/pubmed/32484940
http://dx.doi.org/10.1111/bcp.14406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9328361/
https://www.ncbi.nlm.nih.gov/pubmed/32484940
http://dx.doi.org/10.1111/bcp.14406

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