Cargando…
Therapeutic index of inhaled corticosteroids in asthma: A dose–response comparison on airway hyperresponsiveness and adrenal axis suppression
AIMS: To compare the airway potency, systemic activity and therapeutic index of three inhaled corticosteroids that differ in glucocorticoid receptor binding affinity, physicochemical and pharmacokinetic properties. METHODS: This escalating‐dose, placebo‐controlled, cross‐over study randomised adults...
Autores principales: | Daley‐Yates, Peter, Brealey, Noushin, Thomas, Sebin, Austin, Daren, Shabbir, Shaila, Harrison, Tim, Singh, Dave, Barnes, Neil |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9328361/ https://www.ncbi.nlm.nih.gov/pubmed/32484940 http://dx.doi.org/10.1111/bcp.14406 |
Ejemplares similares
-
Inhaled glucocorticoid-induced metabolome changes in asthma
por: Daley-Yates, Peter, et al.
Publicado: (2022) -
Airway resistance at maximum inhalation as a marker of asthma and airway hyperresponsiveness
por: Mendonça, Nancy T, et al.
Publicado: (2011) -
Inflammatory Mediators in Induced Sputum and Airway Hyperresponsiveness in Cough Variant Asthma during Long-Term Inhaled Corticosteroid Treatment
por: Liu, Meixuan, et al.
Publicado: (2012) -
Daily Inhaled Corticosteroids Treatment Abolishes Airway Hyperresponsiveness to Mannitol in Defence and Police Recruits
por: Lake, Clair D., et al.
Publicado: (2022) -
Size of Inhaled Corticosteroid and Small Airway Inflammation in Asthma
por: Park, Choon-Sik
Publicado: (2017)