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Efficacy and safety of tofacitinib dose de‐escalation and dose escalation for patients with ulcerative colitis: results from OCTAVE Open

BACKGROUND: For patients with UC, flexible maintenance dosing therapy may confer advantages for safety, efficacy, costs and patient preference. Tofacitinib is an oral, small molecule JAK inhibitor for the treatment of UC. AIM: To assess the efficacy and safety of tofacitinib dose de‐escalation and e...

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Detalles Bibliográficos
Autores principales: Sands, Bruce E., Armuzzi, Alessandro, Marshall, John K., Lindsay, James O., Sandborn, William J., Danese, Silvio, Panés, Julián, Bressler, Brian, Colombel, Jean‐Frédéric, Lawendy, Nervin, Maller, Eric, Zhang, Haiying, Chan, Gary, Salese, Leonardo, Tsilkos, Konstantinos, Marren, Amy, Su, Chinyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9328429/
https://www.ncbi.nlm.nih.gov/pubmed/31660640
http://dx.doi.org/10.1111/apt.15555