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HIV-1 latency is established preferentially in minimally activated and non-dividing cells during productive infection of primary CD4 T cells

Latently infected CD4 T cells form a stable reservoir of HIV that leads to life-long viral persistence; the mechanisms involved in establishment of this latency are not well understood. Three scenarios have been proposed: 1) an activated, proliferating cell becomes infected and reverts back to a res...

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Detalles Bibliográficos
Autores principales: Soto, Paula C., Terry, Valeri H., Lewinski, Mary K., Deshmukh, Savitha, Beliakova-Bethell, Nadejda, Spina, Celsa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9328514/
https://www.ncbi.nlm.nih.gov/pubmed/35895672
http://dx.doi.org/10.1371/journal.pone.0271674