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HIV-1 latency is established preferentially in minimally activated and non-dividing cells during productive infection of primary CD4 T cells
Latently infected CD4 T cells form a stable reservoir of HIV that leads to life-long viral persistence; the mechanisms involved in establishment of this latency are not well understood. Three scenarios have been proposed: 1) an activated, proliferating cell becomes infected and reverts back to a res...
Autores principales: | Soto, Paula C., Terry, Valeri H., Lewinski, Mary K., Deshmukh, Savitha, Beliakova-Bethell, Nadejda, Spina, Celsa A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9328514/ https://www.ncbi.nlm.nih.gov/pubmed/35895672 http://dx.doi.org/10.1371/journal.pone.0271674 |
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